2026 NFL Odds Week 5: Lines, Spreads, Results For All 15 Games

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2026 NFL Week 5 Odds: Lines, Spreads, and Results for All 15 Matchups

NFL Week 5 begins with a Thursday matchup between the Buccaneers and Cowboys. As of October 4, here are the betting lines: Cowboys favored by 9.5 points with a moneyline of -600. On Sunday, matchups include Jaguars vs. Eagles, Bears vs. Packers, and Bengals vs. Dolphins, among others, with spreads ranging from -1.5 to -7.5. Betting lines for certain games are still to be determined. The week concludes on Monday with the Rams as 2.5-point favorites against the Bills. For more information, visit bet365 Sportsbook.

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