Cowboys vs. Lions prediction, odds, start time: 2025 NFL Thursday Night Football game picks by proven model


Prediction, odds, and start time for the Cowboys vs. Lions Thursday Night Football game in 2025: Expert picks from a reliable model

The Dallas Cowboys and the Detroit Lions, both fighting for a playoff spot, face off in a crucial NFC matchup on ‘Thursday Night Football.’ The Cowboys are 1.5 games behind the NFC East lead, while the Lions are two games behind in the NFC North. Lions receiver Amon-Ra St. Brown is questionable for the game. The Lions are favored by 3 points with an over/under of 54.5 points. Quarterback Jared Goff leads the Lions offense, while quarterback Dak Prescott leads the Cowboys. SportsLine’s model predicts a high-scoring game with 55 total points. Visit SportsLine for more predictions.

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