Week 16 NFL Picks: Model on 178-129 Roll Predicts Bills vs. Chargers Odds, Line, Spread and Saturday Outcomes
The Los Angeles Chargers will play their first game without head coach Brandon Staley as they face the Buffalo Bills. Interim head coach Giff Smith will lead the 5-9 Chargers against the 8-6 Bills. The Bills are favored to win by 12 points with an over/under of 44.5 points. The model predicts 43 total points, and that one side of the spread will cash in more than 50% of the time. The Chargers have dominated the head-to-head series against the Bills recently, and the Bills may be vulnerable after a tough three-game stretch. SportsLine’s model has identified its picks and predictions for this game.
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